The recent discovery2 that 1-dehydrocortisone and 1-dehydrohydrocortisone possess medicinal properties superior to those of the parent hormones has focussed attention on the 1-dehydro derivatives of other steroidal hormones. I-Dehydrotestoster-I- dehydrodesoxycorticosterone a~ etate,~ 1-dehydro-17-hydroxypr~ gesterone~ and l- dehydro-17-hydroxydesoxycorticosterone acetate5 are all known compounds. The 1- ...
