Abstract-Opening of the aziridine ring in 3-bromo-1-alkyl-1-azoniatricyclo[2.2.1.02,6]heptane bromides by the action of various nucleophiles leads to formation of the corresponding 6-substituted 2-alkyl-2-azabicyclo- [2.2.1]heptanes. ... Compounds of the azabicyclo[2.2.1]heptane series exhibit biological activity [1, 2]. For example, the azabicyclic fragment is present in a number of natural moleculs, such as alkaloids anatoxin and epibatidine and drug cocaine. It ...
