Iodine-alumina catalyzed aza-michael addition under solvent free conditions

…, D Kakati, MS Joseph, JC Sarma

Index: Saikia, Monmi; Kakati, Dwipen; Joseph, Maria Stalin; Sarma, Jadab Chandra Letters in Organic Chemistry, 2009 , vol. 6, # 8 p. 654 - 658

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Citation Number: 13

Abstract

INTRODUCTION The modified form of Michael reaction for conjugate addition of amines to electron deficient alkene is an important class of carbon-nitrogen bond forming reaction in organic synthesis and is usually known as aza-Michael addition [1]. It has been demonstrated to be a powerful tool in organic synthesis owing to its applicability in the synthesis of β-amino ketones, esters, nitriles or amides. β- Amino carbonyl compounds are widely used intermediates for the ...