Reactions of alkyl isocyanates and chlorosulfonyl isocyanate with 1H-tetrazole-5-amine and conversion of reaction products to (1H-tetrazol-5-yl) ureas

…, JP Springer, JM Hirshfield, JA McCauley

Index: Denny, George H.; Cragoe, Edward J.; Rooney, Stanley C.; Springer, James P.; Hirshfield, Jordan M.; McCauley, James A. Journal of Organic Chemistry, 1980 , vol. 45, # 9 p. 1662 - 1665

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Citation Number: 11

Abstract

5-Amino-N-alkyl-1H-tetrazole-1-carboxamides 2-6 were prepared by reaction of alkyl isocyanates with 1H-tetrazol-&amine (1) and thermally isomerized to (lH-tetrazol-5-yl) ureas 7-11. The parent compound of the former series, 5-amino-1H-tetrazole-1-carboxamide (12), was prepared by treatment of 1 with aqueous isocyanic acid, and the parent compound of the latter series,(1H-tetrazol-5-y1) urea (13), was prepared either by heating 12 or by ...