Synthesis and pharmacological characterization of [125I] iodomethyllycaconitine ([125I] Iodo-MLA). A new ligand for the α7 nicotinic acetylcholine receptor

HA Navarro, D Zhong, P Abraham, H Xu…

Index: Navarro, Hernan A.; Zhong, Desong; Abraham, Philip; Xu, Heng; Carroll, F. Ivy Journal of Medicinal Chemistry, 2000 , vol. 43, # 2 p. 142 - 145

Full Text: HTML

Citation Number: 31

Abstract

Since the nicotinic acetylcholine receptors (nAChRs) have been targeted for the development of drugs for cognitive function, Parkinson's disease, analgesia, inflammatory bowel disorder, schizophrenia, anxiety, depression, Tourette's syndrome, and smoking cessation, considerable effort has been directed toward the identification and characterization of radioligands for this receptor system. 1, 2 Two major classes of ...

Asymmetric syntheses of moiramide B and andrimid

[Davies, Stephen G.; Dixon, Darren J. Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 17 p. 2635 - 2643]

Asymmetric hydrogenation of olefins with aprotic oxygen func...

[Ohta, Tetsuo; Miyake, Tsutomu; Seido, Nobuo; Kumobayashi, Hidenori; Takaya, Hidemasa Journal of Organic Chemistry, 1995 , vol. 60, # 2 p. 357 - 363]

Asymmetric syntheses of moiramide B and andrimid

[Davies, Stephen G.; Dixon, Darren J. Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 17 p. 2635 - 2643]

Acylation of lycoctonine: semi-synthesis of inuline, delsemi...

[Blagbrough, Ian S.; Coates, Philippa A.; Hardick, David J.; Lewis, Terence; Rowan, Michael G.; Wonnacott, Susan; Potter, Barry V. L. Tetrahedron Letters, 1994 , vol. 35, # 46 p. 8705 - 8708]