Tetrahedron letters

A mild synthesis of N-functionalised bromomaleimides, thiomaleimides and bromopyridazinediones

…, C Marculescu, TM Tran, V Chudasama, A Maruani…

Index: Castaneda, Lourdes; Wright, Zoe V.F.; Marculescu, Cristina; Tran, Trang M.; Chudasama, Vijay; Maruani, Antoine; Hull, Elizabeth A.; Nunes, Joao P.M.; Fitzmaurice, Richard J.; Smith, Mark E.B.; Jones, Lyn H.; Caddick, Stephen; Baker, James R. Tetrahedron Letters, 2013 , vol. 54, # 27 p. 3493 - 3495

Full Text: HTML

Citation Number: 22

Abstract

Bromomaleimides are useful building blocks in synthesis and powerful reagents for the selective chemical modification of proteins. A mild new synthesis of these reagents is described, along with the convenient transferability of the approach to dithiomaleimides and bromopyridazinediones.