Modification of a promiscuous inhibitor shifts the inhibition from γ-secretase to FLT-3

GMO Amombo, T Kramer, FL Monte, S Göring…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 24 p. 7634 - 7640

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Abstract

... Bioorganic & Medicinal Chemistry Letters. Volume 22, Issue 24, 15 December 2012, Pages 7634–7640. Cover image Cover image. ... a Clemens Schöpf-Institute of Organic Chemistry and Biochemistry, Technische Universität Darmstadt, Petersenstr. ...