Syntheses of isotopically labeled 4??[1??(3, 5, 5, 8, 8??pentamethyl??5, 6, 7, 8??tetrahydro??2??naphthyl) ethenyl] benzoic acid (LGD1069), a potent retinoid x receptor?? …

L Zhang, BA Badea, D Enyeart…

Index: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 36, # 7 p. 701 - 712

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Citation Number: 7

Abstract

Page 1. Journal of Labelled Cornpoutids and Radiopharmaceuticals-Vol. XXXVI, No. 7 ... 14 was treated with 2 equivalents of nBuLi at -78 OC followed by addition of the appropriate isotopically labeled methyl iodine. ...

 Related Synthetic Route
1,1,4,4,6-pentamethyl-1,4-dihydronaphthalene Structure

167958-79-4

1,1,4,4,6-penta...

~80%

1,1,4,4,6-PENTAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE Structure

6683-48-3

1,1,4,4,6-PENTA...

2(1H)-Naphthalenone, 3,4-dihydro-1,1,4,4,7-pentamethyl- Structure

29020-85-7

2(1H)-Naphthale...

~%

1,1,4,4,6-PENTAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE Structure

6683-48-3

1,1,4,4,6-PENTA...

1,1,4,4,7-pentamethyl-2-hydroxy-1,2,3,4-tetrahydronaphthalene Structure

167958-78-3

1,1,4,4,7-penta...

~%

1,1,4,4,6-PENTAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE Structure

6683-48-3

1,1,4,4,6-PENTA...

2(1H)-Naphthalenone, 3,4-dihydro-1,1,4,4,7-pentamethyl- Structure

29020-85-7

2(1H)-Naphthale...

~%

Bexarotene Structure

153559-49-0

Bexarotene

Toluene Structure

108-88-3

Toluene

~%

Bexarotene Structure

153559-49-0

Bexarotene

1,1,4,4,6-pentamethyl-1,4-dihydronaphthalene Structure

167958-79-4

1,1,4,4,6-penta...

~%

Bexarotene Structure

153559-49-0

Bexarotene

1,1,4,4,7-pentamethyl-2-hydroxy-1,2,3,4-tetrahydronaphthalene Structure

167958-78-3

1,1,4,4,7-penta...

~%

Bexarotene Structure

153559-49-0

Bexarotene

2(1H)-Naphthalenone, 3,4-dihydro-1,1,4,4,7-pentamethyl- Structure

29020-85-7

2(1H)-Naphthale...

~%

Methyl 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoate Structure

153559-45-6

Methyl 4-[(5,6,...

Toluene Structure

108-88-3

Toluene

~%

Methyl 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoate Structure

153559-45-6

Methyl 4-[(5,6,...

1,1,4,4,6-pentamethyl-1,4-dihydronaphthalene Structure

167958-79-4

1,1,4,4,6-penta...

~%

Methyl 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoate Structure

153559-45-6

Methyl 4-[(5,6,...

1,1,4,4,7-pentamethyl-2-hydroxy-1,2,3,4-tetrahydronaphthalene Structure

167958-78-3

1,1,4,4,7-penta...

~%

Methyl 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoate Structure

153559-45-6

Methyl 4-[(5,6,...


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