Russian Journal of General Chemistry

1-(Pyrimidin-4-yl) pyrazol-5 (4H)-one derivatives: I. Synthesis of 3-methyl-1-(6-methyl-2-methylsulfanylpyrimidin-4-yl)-pyrazol-5-ol and specificity of its Knoevenagel …

AV Erkin, VI Krutikov

Index: Erkin; Krutikov Russian Journal of General Chemistry, 2011 , vol. 81, # 2 p. 392 - 396

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Citation Number: 3

Abstract

Abstract 3-Methyl-1-(6-methyl-2-methylsulfanylpyrimidin-4-yl)-1 H-pyrazol-5-ol available via cyclocondensation of 6-methyl-2-methylsulfanylpyrimidin-4-ylhydrazine with ethyl acetoacetate reacted with aromatic aldehydes to give two kinds of products, 4- arylmethylidene-5-oxo-4, 5-dihydropyrazole and arylbis (5-hydroxypyrazol-4-yl) methane derivatives, depending on the substituent in the aromatic aldehyde.