Abstract The bromination of 2, 1, 3-benzothiadiazoles in 47% hydrobromic acid at elevated temperature has led to a general preparative method for the synthesis in high yield of otherwise difficulty accessible brominated 2, 1, 3-benzothiadiazoles. The typical addition reaction is apparently eliminated under these reaction conditions and substitution takes place exclusively. Bromination of 2, 1, 3-benzothiadiazole occurs successively at positions ...
![4-BROMO-7-BROMOMETHYL-BENZO[1,2,5]THIADIAZOLE Structure](https://image.chemsrc.com/caspic/158/2255-78-9.png)