e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Aryl coupling reactions of pyrazolo [3, 4-d] pyrimidin-4-yl radicals

JB Press, NH Eudy, GO Morton

Index: Journal of Organic Chemistry, , vol. 48, # 24 p. 4605 - 4611

Full Text: HTML

Citation Number: 8

Abstract

... Found: C, 67.35; H, 5.02; N, 24.39. (15) For discussions of isomer distribution a~ a result of radical attacks on aromatic systems see: (a) Fleming, I. “Frontiers Orbitals and Organic Chemical Reactions”; Wiley: New York, 1976; pp 191-194. ... J. Org. Chem., Vol. 48, No. ...

7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraen-5-amine Structure

7,9-dimethyl-2,...

~%

4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine Structure

4-Chloro-1,3-di...

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N-(1,3-dimethylpyrazolo[3,4-d]pyrimidin-4-yl)diacetamide Structure

N-(1,3-dimethyl...

~%

4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine Structure

4-Chloro-1,3-di...

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N-(1,3-dimethylpyrazolo(3,4-d)pyrimidin-4-yl)acetamide Structure

N-(1,3-dimethyl...

~%

4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine Structure

4-Chloro-1,3-di...

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1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

~69%

4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine Structure

4-Chloro-1,3-di...

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7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraen-5-amine Structure

7,9-dimethyl-2,...

~%

1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

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N-(1,3-dimethylpyrazolo[3,4-d]pyrimidin-4-yl)diacetamide Structure

N-(1,3-dimethyl...

~%

1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

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7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraen-5-amine Structure

7,9-dimethyl-2,...

Pentyl nitrite Structure

~9%

1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

1,3-dimethyl-4-phenylpyrazolo(3,4-d)pyrimidine Structure

1,3-dimethyl-4-...

Detail Learn More

7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraen-5-amine Structure

7,9-dimethyl-2,...

~22%

1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraene Structure

7,9-dimethyl-2,...

1,3-dimethyl-4-(pentyloxy)-1H-pyrazolo(3,4-d)pyrimidine Structure

1,3-dimethyl-4-...

Detail Learn More

7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraen-5-amine Structure

7,9-dimethyl-2,...

Chlorobenzene Structure

~41%

1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

1,3-dimethyl-4-(pentyloxy)-1H-pyrazolo(3,4-d)pyrimidine Structure

1,3-dimethyl-4-...

Detail Learn More

N-(1,3-dimethylpyrazolo(3,4-d)pyrimidin-4-yl)acetamide Structure

N-(1,3-dimethyl...

~%

1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

Learn More

7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraen-5-amine Structure

7,9-dimethyl-2,...

Toluene Structure

~22%

1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraene Structure

7,9-dimethyl-2,...

Detail Learn More

7,9-dimethyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraen-5-amine Structure

7,9-dimethyl-2,...

benzene Structure

~9%

1,3-Dimethyl-1,5-dihydro-4H-pyrazolo-[3,4-d]pyrimidin-4-one Structure

1,3-Dimethyl-1,...

1,3-dimethyl-4-phenylpyrazolo(3,4-d)pyrimidine Structure

1,3-dimethyl-4-...

Detail Learn More

1-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine Structure

1-Methyl-1H-pyr...

~59%

1-methyl-4-phenylpyrazolo[3,4-d]pyrimidine Structure

1-methyl-4-phen...

1-METHYL-1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE Structure

1-METHYL-1,5-DI...

1-methyl-4-(pentyloxy)-1H-pyrazolo(3,4-d)pyrimidine Structure

1-methyl-4-(pen...

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1-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine Structure

1-Methyl-1H-pyr...

benzene Structure

~56%

1-methyl-4-phenylpyrazolo[3,4-d]pyrimidine Structure

1-methyl-4-phen...

1-METHYL-1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE Structure

1-METHYL-1,5-DI...

Detail Learn More