The formation of the C3-symmetrical 2, 11, 20-triaza [3.3. 3](2, 6) pyridinophane 1 was undertaken with the aim of improving the synthesis of this highly desirable macrocycle, with the future aim of functionalizing 1 with amide pendent arms for the recognition of lanthanide ions. The synthesis of 1 involves the stepwise transformation of pyridine-2, 6-dicarboxylic acid into two key intermediates; N, N-bis [(6-hydroxymethyl) pyridin-2-yl]-p-tosylamide 7 ...
![[6-(bromomethyl)pyridin-2-yl]methanol Structure](https://image.chemsrc.com/caspic/119/40054-01-1.png)