Identification of new γ-hydroxybutenolides that preferentially inhibit the activity of mPGES-1

R De Simone, I Bruno, R Riccio, K Stadler…

Index: Bioorganic and Medicinal Chemistry, , vol. 20, # 16 p. 5012 - 5016

Full Text: HTML

Citation Number: 10

Abstract

... Bioorganic & Medicinal Chemistry. ... University Jena, Philosophenweg 14, D-07743 Jena, Germany; d Chair of Pharmaceutical/Medicinal Chemistry, Pharmaceutical Institute, University ... Continuing our investigations in medicinal chemistry area, in the recent years our studies 16, 17 ...

 Related Synthetic Route
Pinacol Structure

76-09-5

Pinacol

~%

N-benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide Structure

1048647-68-2

N-benzyl-3-(4,4...

3-Carboxyphenylboronic acid Structure

25487-66-5

3-Carboxyphenyl...

~%

N-benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide Structure

1048647-68-2

N-benzyl-3-(4,4...

Pyrrolidine Structure

123-75-1

Pyrrolidine

4-Carboxyphenylboronic Acid Pinacol Ester Structure

180516-87-4

4-Carboxyphenyl...

~86%

PYRROLIDIN-1-YL(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)METHANONE Structure

1073353-55-5

PYRROLIDIN-1-YL...

Pinacol Structure

76-09-5

Pinacol

~%

PYRROLIDIN-1-YL(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)METHANONE Structure

1073353-55-5

PYRROLIDIN-1-YL...

p-Boronobenzoic acid Structure

14047-29-1

p-Boronobenzoic acid

~%

PYRROLIDIN-1-YL(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)METHANONE Structure

1073353-55-5

PYRROLIDIN-1-YL...

Pinacol Structure

76-09-5

Pinacol

~%

N-benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide Structure

1073353-57-7

N-benzyl-4-(4,4...

p-Boronobenzoic acid Structure

14047-29-1

p-Boronobenzoic acid

~%

N-benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide Structure

1073353-57-7

N-benzyl-4-(4,4...

Pinacol Structure

76-09-5

Pinacol

~%

PYRROLIDIN-1-YL(3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)METHANONE Structure

1073353-61-3

PYRROLIDIN-1-YL...

3-Carboxyphenylboronic acid Structure

25487-66-5

3-Carboxyphenyl...

~%

PYRROLIDIN-1-YL(3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)METHANONE Structure

1073353-61-3

PYRROLIDIN-1-YL...

4-Carboxyphenylboronic Acid Pinacol Ester Structure

180516-87-4

4-Carboxyphenyl...

N-Boc-piperazine Structure

57260-71-6

N-Boc-piperazine

~69%

1-BOC-4-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZOYL]-PIPERAZINE Structure

864754-13-2

1-BOC-4-[4-(4,4...

Pinacol Structure

76-09-5

Pinacol

~%

1-BOC-4-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZOYL]-PIPERAZINE Structure

864754-13-2

1-BOC-4-[4-(4,4...


Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved