Organic letters

Oxidative Cyclization of β-Hydroxyenones with Palladium (II): A Novel Entry to 2, 3-Dihydro-4 H-pyran-4-ones

M Reiter, S Ropp, V Gouverneur

Index: Reiter, Maud; Ropp, Sandrine; Gouverneur, Veronique Organic Letters, 2004 , vol. 6, # 1 p. 91 - 94

Full Text: HTML

Citation Number: 48

Abstract

A palladium (II)-mediated oxidative cyclization was found to be effective for the preparation of structurally diverse 2, 3-dihydro-4 H-pyran-4-ones from the corresponding β- hydroxyenones. Attractive features of this transformation include the ready availability of the starting enones, the regiocontrol, and the easy access of enantiopure 2, 3-dihydro-4 H-pyran- 4-one from the corresponding enantiopure enone.