Synthesis and diuretic profile of 3-(3-amino-1, 2, 4-oxadiazol-5-yl)-5-chloro-2, 6-pyrazinediamine, an amiloride-type diuretic

JWH Watthey, M Desai, R Rutledge…

Index: Journal of Medicinal Chemistry, , vol. 23, # 6 p. 690 - 692

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Citation Number: 29

Abstract

... The authors also thank Dr. MR Boots of the Medical College of Virginia for helpful discussions. This work was supported in part by a grant from Hoff- man-La Roche, Inc. ... Notes Table I. Diuretic Activity in the Rat Journal of Medicinal Chemistry, 1980, Vol. 23, No. 6 691 ...