The Journal of Organic Chemistry

Imidazo [4, 5-d] pyridazines. I. Synthesis of 4, 7-Disubstituted Derivatives1

RN CASTLE, WS SEESE

Index: Castle; Seese Journal of Organic Chemistry, 1958 , vol. 23, p. 1534,1536

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Citation Number: 43

Abstract

Dimethiil imidazole-1.5-dicarboxulate (11). I4 This comoound wis prepared according to procedure b of Baxter ind Spring. 15 Further purification from hot water gave colorless crystals, melting at 207". Anal. Calcd. for C, HsN204: C, 45.56; H, 4.37. Found: C, 45.76; H,

1-amino-4-benzylphthalazines as orally bioavailable smoothen...

[Miller-Moslin, Karen; Peukert, Stefan; Jain, Rishi K.; McEwan, Michael A.; Karki, Rajesh; Llamas, Luis; Yusuff, Naeem; He, Feng; Li, Yanhong; Sun, Yingchuan; Dai, Miao; Perez, Lawrence; Michael, Walter; Sheng, Tao; Lei, Huangshu; Zhang, Rui; Williams, Juliet; Bourret, Aaron; Ramamurthy, Arun; Yuan, Jing; Guo, Ribo; Matsumoto, Melissa; Vattay, Anthony; Maniara, Wieslawa; Amaral, Adam; Dorsch, Marion; Kelleher III, Joseph F. Journal of Medicinal Chemistry, 2009 , vol. 52, # 13 p. 3954 - 3968]