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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

The Journal of Organic Chemistry

Imidazo [4, 5-d] pyridazines. I. Synthesis of 4, 7-Disubstituted Derivatives1

RN CASTLE, WS SEESE

Index: Castle; Seese Journal of Organic Chemistry, 1958 , vol. 23, p. 1534,1536

Full Text: HTML

Citation Number: 43

Abstract

Dimethiil imidazole-1.5-dicarboxulate (11). I4 This comoound wis prepared according to procedure b of Baxter ind Spring. 15 Further purification from hot water gave colorless crystals, melting at 207". Anal. Calcd. for C, HsN204: C, 45.56; H, 4.37. Found: C, 45.76; H,

 Related Synthetic Route
Dimethyl 4,5-imidazoledicarboxylate Structure

3304-70-9

Dimethyl 4,5-im...

~%

4,7-Dichloro-1H-imidazo[4,5-d]pyridazine Structure

17998-43-5

4,7-Dichloro-1H...

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1H-Imidazole-4,5-dicarboxylicacid, dihydrazide (9CI) Structure

5423-20-1

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4,7-Dichloro-1H-imidazo[4,5-d]pyridazine Structure

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3a,7a-Dihydro-1H-imidazo(4,5-d)pyridazine-4,7-dione Structure

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N,N-Dimethylaniline

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4H-Imidazo[4,5-d]pyridazin-4-one,7-chloro-1,5-dihydro Structure

28683-00-3

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4,7-Dichloro-1H-imidazo[4,5-d]pyridazine Structure

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Ethanol Structure

64-17-5

Ethanol

4,7-bis(methylsulfanyl)-1H-imidazo[4,5-d]pyridazine Structure

98277-49-7

4,7-bis(methyls...

~%

3,4,7,9-tetrazabicyclo[4.3.0]nona-2,4,7,10-tetraene-2,5-diamine Structure

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Dimethyl 4,5-imidazoledicarboxylate Structure

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4H-Imidazo[4,5-d]pyridazin-4-one,7-chloro-1,5-dihydro Structure

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3a,7a-Dihydro-1H-imidazo(4,5-d)pyridazine-4,7-dione Structure

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4H-Imidazo[4,5-d]pyridazin-4-one,7-chloro-1,5-dihydro Structure

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3a,7a-Dihydro-1H-imidazo(4,5-d)pyridazine-4,7-dione Structure

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1H-Imidazo(4,5-d)pyridazine-4,7-dithiol Structure

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Dimethyl 4,5-imidazoledicarboxylate Structure

3304-70-9

Dimethyl 4,5-im...

~%

1H-Imidazo(4,5-d)pyridazine-4,7-dithiol Structure

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1H-Imidazole-4,5-dicarboxylicacid, dihydrazide (9CI) Structure

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~%

1H-Imidazo(4,5-d)pyridazine-4,7-dithiol Structure

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1H-Imidazo(4,5-...

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1-amino-4-benzylphthalazines as orally bioavailable smoothen...

[Miller-Moslin, Karen; Peukert, Stefan; Jain, Rishi K.; McEwan, Michael A.; Karki, Rajesh; Llamas, Luis; Yusuff, Naeem; He, Feng; Li, Yanhong; Sun, Yingchuan; Dai, Miao; Perez, Lawrence; Michael, Walter; Sheng, Tao; Lei, Huangshu; Zhang, Rui; Williams, Juliet; Bourret, Aaron; Ramamurthy, Arun; Yuan, Jing; Guo, Ribo; Matsumoto, Melissa; Vattay, Anthony; Maniara, Wieslawa; Amaral, Adam; Dorsch, Marion; Kelleher III, Joseph F. Journal of Medicinal Chemistry, 2009 , vol. 52, # 13 p. 3954 - 3968]

Detail Synthetic Route


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