e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Journal of Fluorine Chemistry

Regioselective synthesis of 1-methyl-3-hydroxy-5-perfluoroalkylpyrazoles by the addition of methylhydrazine to perfluoroalkylacetylenic esters

BC Hamper

Index: Journal of Fluorine Chemistry, , vol. 48, # 1 p. 123 - 131

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Citation Number: 32

Abstract

... Download full text in PDF. Journal of Fluorine Chemistry, 48 (1990) 123-131 123 Received ... RESULTS AND DISCUSSION In the course of exploring the chemistry of perfluoroalkylacetylenic esters 1 [9 ... a triplet for C5 in the proton decoupled spectrum due to fluorine coupling to the ...

2-Butynoic acid,4,4,4-trifluoro-, ethyl ester Structure

2-Butynoic acid...

monomethylhydrazine Structure

monomethylhydrazine

~5%

1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-ol Structure

1-Methyl-3-(tri...

1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3(2H)-one Structure

1-Methyl-5-(tri...

2-Butynoic acid,4,4,4-trifluoro-, ethyl ester Structure

2-Butynoic acid...

monomethylhydrazine Structure

monomethylhydrazine

~93%

1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-ol Structure

1-Methyl-3-(tri...

1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3(2H)-one Structure

1-Methyl-5-(tri...

Synthesis and 13C NMR of (trifluoromethyl) hydroxypyrazoles

[Journal of Heterocyclic Chemistry, , vol. 27, # 2 p. 243 - 245]

Regiospecific synthesis of polyfluorinated heterocycles

[Martins, Marcos A.P.; Pereira, Claudio M.P.; Zimmermann, Nilo E.K.; Cunico, Wilson; Moura, Sidnei; Beck, Paulo; Zanatta, Nilo; Bonacorso, Helio G. Journal of Fluorine Chemistry, 2003 , vol. 123, # 2 p. 261 - 265]