Design and synthesis of piperazinylpyridine derivatives as novel 5-HT1A agonists/5-HT3 antagonists for the treatment of irritable bowel syndrome (IBS)

A Asagarasu, T Matsui, H Hayashi, S Tamaoki…

Index: Chemical and Pharmaceutical Bulletin, , vol. 57, # 1 p. 34 - 42

Full Text: HTML

Citation Number: 14

Abstract

... Bull. 57(1) 34—42 (2009) © 2009 Pharmaceutical Society of Japan ∗ To whom correspondence should be addressed. e-mail: asagarasu-a@aska-pharma.co.jp Fig. ... Chemical shifts are re- ported in ppm relative to tetramethylsilane, using the following abbrevia- 38 Vol. ...