ACS combinatorial science

Unprecedented one-pot chemocontrolled entry to thioxoimidazolidinones and aminoimidazolones: synthesis of kinase inhibitor Leucettamine B

M Selvaraju, CM Sun

Index: Maiti, Barnali; Chanda, Kaushik; Selvaraju, Manikandan; Tseng, Chih-Chung; Sun, Chung-Ming ACS Combinatorial Science, 2013 , vol. 15, # 6 p. 291 - 297

Full Text: HTML

Citation Number: 3

Abstract

A novel and highly chemoselective protocol for the construction of thioxoimidazolidinone and aminoimidazolone frameworks was explored, and the influence of the reaction conditions on product formation was studied to establish two distinct approaches for their