Synthesis and antitumor activity of 2, 3, 10, 11-tetramethoxy-5, 6, 7, 8, 13, 13a-hexahydroprotoberberines and their B-seco analogs

…, NM Sazonova, GS Grekova, SG Kalistratov…

Index: Sladkov, V. I.; Sazonova, N. M.; Grekova, G. S.; Kalistratov, S. G.; Sokolova, A. S.; et al. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 1 p. 47 - 50 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 1 p. 50 - 53

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Citation Number: 5

Abstract

The proceeding of the reactions and the purity of the products was checked by thin-layer chromatography on Silufol UV-254 plates (Kavalier, Czechoslovakia). Spots were visualized under UV light. Hydrochlorides Ia, Va, Xa, and XIa, were obtained by precipitation with dry diethyl ether from ethanolic hydrogen chloride solutions. Calculated and found values of elemental analyses corresponded.