Organic letters

An efficient direct amination of cyclic amides and cyclic ureas

ZK Wan, S Wacharasindhu, E Binnun, T Mansour

Index: Organic Letters, , vol. 8, # 11 p. 2425 - 2428

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Citation Number: 58

Abstract

... Volume: Page: ... Organic Letters. ... 6 was synthesized in just one step from hypoxanthine 4a in 90% yield (eq 1, Scheme 4). Meanwhile, direct amination of 1-methylguanine 7, followed by one-pot reductive amination and desilylation, provided olomoucine 8 in 80 ...