Tetrahedron

Synthesis of 1, 3-disubstituted naphtho [2, 3-c] pyran-5, 10-diones

TN Van, B Kesteleyn, N De Kimpe

Index: Nguyen Van, Tuyen; Kesteleyn, Bart; De Kimpe, Norbert Tetrahedron, 2001 , vol. 57, # 19 p. 4213 - 4219

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Citation Number: 27

Abstract

Two convenient and simple methods for the synthesis of 1, 3-disubstituted naphtho [2, 3-c] pyran-5, 10-diones, which involve the introduction of acylmethyl groups onto 2-(1- hydroxyethyl)-1, 4-naphthoquinones and subsequent base-and acid-induced ring closure, were developed.