The detrimental effect of orotic acid substitution in the peptide nucleic acid strand on the stability of PNA2: NA triple helices

RHE Hudson, F Wojciechowski

Index: Canadian Journal of Chemistry, , vol. 83, # 10 p. 1731 - 1740

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Citation Number: 8

Abstract

... Solvents for solu- tion-phase chemistry were obtained from Caledon Labora- tories Ltd. ... The oxidation of 5- hydroxymethyluracil to the carboxylic acid may be achieved in one step, but we found that 5-formyluracil cleanly precip- © 2005 NRC Canada 1736 Can. J. Chem. Vol. ...