Synthesis of Novel Piperazine Phosphoramidate Analogues of 2-Arylquinolones

…, X Chen, L Qu, J Yuan, H Li, Y Zhao

Index: Qu, Zhibo; Chen, Xiaolan; Qu, Lingbo; Yuan, Jinwei; Li, Huina; Zhao, Yufen Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 7 p. 1516 - 1520

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Abstract

A series of novel piperazine phosphoramidate derivatives of 2-arylquinolones were synthesized to improve their physicochemical and biological properties through a facile phosphorylating reaction. Their structures were elucidated by NMR, ESI MS, and HRMS. ... A series of novel piperazine phosphoramidate derivatives of 2-arylquinolones were synthesized to improve their physicochemical and biological properties through a facile phosphorylating reaction. Their structures were ...