Local Anesthetics. III. Aroyl Derivatives of β-Methyl-β-monoalkylamino Propanols

JS Pierce, RD Gano, JM Lukeman

Index: Pierce; Gano; Lukeman Journal of the American Chemical Society, 1948 , vol. 70, p. 255

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Citation Number: 2

Abstract

In previous papers2e3 from this Laboratory, the preparation of alkoxybenzoates of P- monoalkylaminoethanols, p-methyl-P-monoalkylaminopro-panols and P- monoalkylaminobutanols was described. Some of the products were found to be effective as local anesthetics. It thus seemed advisable to prepare esters of the above@-secondary aminoalkanols with other aromatic acids. Therefore, we have prepared cinnamates, ...