Abstract Three different methods of acetonation of d-mannitol using (a) acetone and zinc chloride,(b), 2, 2-dimethoxypropane, 1, 2-dimethoxyethane, and tin (II) chloride, and (c) 2- methoxypropene, N, N-dimethylformamide, and p-toluenesulfonic acid were studied in detail and compared, using gas-liquid chromatographic techniques. In each reaction, isomeric diacetals are formed, but method a gives the 1, 2: 5, 6-diacetal in the highest yield (63%). ...
![(R)-1-[(4R,4'R)-2,2,2',2'-Tetramethyl-4α,4'β-bi[1,3-dioxolane]-5β-yl]ethane-1,2-diol Structure](https://image.chemsrc.com/caspic/159/38145-93-6.png)