Asymmetric palladium-catalyzed hydrosilylation of styrenes using efficient chiral spiro phosphoramidite ligands

…, JH Xie, GH Hou, WJ Shi, LX Wang, QL Zhou

Index: Guo, Xun-Xiang; Xie, Jian-Hua; Hou, Guo-Hua; Shi, Wen-Jian; Wang, Li-Xin; Zhou, Qi-Lin Tetrahedron Asymmetry, 2004 , vol. 15, # 14 p. 2231 - 2234

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Citation Number: 36

Abstract

Asymmetric hydrosilylation of styrene derivatives with trichlorosilane in the presence of palladium complexes of chiral spiro phosphoramidites provided 1-aryl-1-silylalkanes as single regioisomers in high yields, which have been oxidized with hydrogen peroxide to give the corresponding chiral alcohols in up to 99.1% ee.