Functionalized pyrimidines 1, 1a, 1b, 1c, 1d, 1e, 1f and 1g play an important role as analgesic, 1a antihypertensive, 1b antipyretic, 1c and anti-inflammatory drugs, 1d as pesticides, 1e herbicides, 1f and plant growth regulators. 1g For example, the naturally occurring l-lathyrine shows a wide range of biological activity, such as pollen growth inhibition, antitumor, and hypoglycaemic activity (Fig. 1). 2, 2a and 2b Although pyrimidine ...
