Indium-Mediated Asymmetric Barbier-Type Propargylations: Additions to Aldehydes and Ketones and Mechanistic Investigation of the Organoindium Reagents

TD Haddad, LC Hirayama, JJ Buckley…

Index: Wu, Shihui; Huang, Bangzhou; Gao, Xiang Synthetic Communications, 1990 , vol. 20, # 9 p. 1279 - 1286

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Citation Number: 18

Abstract

... Volume: Page: ... 3, 3, –20, THF, 89, 83. ... Table 2, entries 7 and 8). The α,β-unsaturated aldehyde, cinnamaldehyde, produced the corresponding homopropargylic alcohol product (4i) in good yield (71%) and enantioselectivity (75% ee) (Table 2, entry 9). Finally, the ...