Molecules

A simplified liquid chromatography-mass spectrometry assay for artesunate and dihydroartemisinin, its metabolite, in human plasma

P Teja-Isavadharm, D Siriyanonda, R Siripokasupkul…

Index: Molecules, , vol. 15, # 12 p. 8747 - 8768

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Citation Number: 16

Abstract

... 7 Injection (µl) NA 25 30 NA 5 5 8 Plasma volume (µl) 50-100 500 1000 1000 50 (96-well plate) 100 ... Protein precipitate- Plasma:ACN=1:2 (ice-cold) 10 Reconstitute/final vol (µl) IS in 50%ACN + 50 µl of water/NA 200, MP 250, 50%ACN 60, MeOH 200 300 ... Molecules 2010, 15 ...