Synthesis and characterisation of a novel tubulin-directed DO3A–colchicine conjugate with potential theranostic features

NJ Wardle, T Kalber, JD Bell, SWA Bligh

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 11 p. 3346 - 3348

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Citation Number: 3

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... made to achieve such conjugate structures, exemplified in investigations of a 90 Y-labelled DOTA conjugate with trimethylcolchicinic acid and a 99m Tc-labelled ethylenedicysteine conjugate with colchicine itself in nuclear medicine. ...