Synthesis of chromogenic substrates for the assay of aminopeptidase activity

TP Goldstein, RE Plapinger, MM Nachlas…

Index: Goldstein,T.P. et al. Journal of Medicinal and Pharmaceutical Chemistry, 1962 , vol. 5, p. 852 - 857

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Citation Number: 17

Abstract

Xlt hough the enzymes aminopolypep tidasc: amiiiodipeptidascl, iLnd leucyl aminopeptidase have been de~ cribed~*~~-j, it is not, knotvii whether there exists one non- specific aminopeptidase or many aminopeptidases specific for each amino acid. Since a. biochemical and histochemical method for leucyl aminopeptidase has been described iitilizing~-leucyl-2-naphthylamide as the subst, r: ite,” 6 a series of tiaph thylamides of ...