Nucleophilic addition to 2-imidazolines. A ketone synthesis via tetrahydrofolate coenzyme models

MW Anderson, RCF Jones, J Saunders

Index: Anderson, Michael W.; Jones, Raymond C. F.; Saunders, John Journal of the Chemical Society, Chemical Communications, 1982 , # 5 p. 282 - 283

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Abstract

2-Alkyl-1 -benzyl-3-methyl-2-imidazolinium salts with Grignard reagents give addition products that are hydrolysed to ketones; 2-imidazolines and 2-imidazolinium salts with hydride reagents afford N-alkylated 1,2 - d ia mi noet ha nes. ... The coenzyme N6,N10-methenyltetrahydrofolic acid uses a ... 2-imidazoline ring in the transfer of functionalised carbon at ... (Scheme 1) mimics these processes. In order to extend this ... Published on 01 January 1982. Downloaded ...