The synthesis of deuterium??labelled cocaine, cocaethylene and metabolites

ET Everhart, P Jacob, J Mendelson…

Index: Everhart, E. Thomas; Jacob III, Peyton; Mendelson, John; Jones, Reese T. Journal of Labelled Compounds and Radiopharmaceuticals, 1999 , vol. 42, # 13 p. 1265 - 1275

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Citation Number: 9

Abstract

Abstract We describe the syntheses of benzoylecgonine,(1, 1, 1-2 H 3) methyl ester [(2 H 3) cocaine],(2 H 5) benzoylecgonine,(2 H 5) benzoylecgonine methyl ester [(2 H 5) cocaine], benzoylecgonine (2, 2, 2-2 H 3) ethyl ester [(2 H 3) cocaethylene],(2 H 5) benzoylecgonine ethyl ester [(2 H 5) cocaethylene],(2 H 5) benzoylecgonine (2, 2, 2-2 H 3) ethyl ester [(2 H 8) cocaethylene], ecgonine (1, 1, 1-2 H 3) methyl ester, ecgonine (2, 2, 2-2 H 3) ethyl ester, ...