An Expeditious Synthesis of Some Novel N-Pyridyl-1, 4-dihydro-4-oxo-3-quinoline Carboxylic Acids/Amides as Potential CB2 Cannabinoid Receptor Agonists

CN Reddy, GV Subbaraju, HR Mohan…

Index: Reddy, C. Naveenkumar; Subbaraju, Gottumukkala V.; Mohan, H. Rama; Rao, D. Muralimohan Asian Journal of Chemistry, 2011 , vol. 23, # 7 p. 2981 - 2988

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Abstract

Abstract An expeditious synthesis of novel N-pyridyl-1, 4-dihydro-4-oxo-3-quinoline carboxylic acids (9a-e) in 5 steps and N-pyridyl-4-oxo-1, 4-dihydroquinoline-3- carboxamides (1a-m) were developed in six steps from a commercially available 2-bromo benzoic acid.