Total Synthesis of (±)-Glabridin

WH Ji, QS Gao, YL Lin, HM Gao, X Wang…

Index: Ji, Wen-Hua; Gao, Qian-Shan; Lin, Yun-Liang; Gao, Hong-Mei; Wang, Xiao; Geng, Yan-Ling Synthetic Communications, 2014 , vol. 44, # 4 p. 540 - 546

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Abstract

An efficient formal synthesis of (±)-glabridin was accomplished in 10 steps from resorcinol using Raney Ni to reduce carbon–carbon double bonds in α,β-unsaturated carbonyl compound as the key step. ... [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource(s): Full experimental and spectral details.] ... An efficient formal synthesis of (±)-glabridin was accomplished in ...