“Click-fluors”: Modular Fluorescent Saccharide Sensors Based on a 1, 2, 3-Triazole Ring

DK Scrafton, JE Taylor, MF Mahon…

Index: Scrafton, David K.; Taylor, James E.; Mahon, Mary F.; Fossey, John S.; James, Tony D. Journal of Organic Chemistry, 2008 , vol. 73, # 7 p. 2871 - 2874

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Citation Number: 83

Abstract

A carbohydrate sensing “click-fluor” is reported which displays a nontypical binding preference with sample saccharides. That a fluorescent sensor is generated as a result of triazole formation (click reaction), rather than simply bringing the sensor and reporter units together via a triazole linkage, and the potential applicability of the wide range of easily accessible acetylene units means a simple strategy for the development of modular ...