Tetrahedron letters

Stereochemically controlled synthesis of unsaturated acids via diphenylphosphinoyl (Ph 2 PO)-ketoacids

D Levin, S Warren

Index: Levin, Daniel; Warren, Stuart Tetrahedron Letters, 1985 , vol. 26, # 4 p. 505 - 508

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Citation Number: 11

Abstract

Abstract Acylation of phosphine oxide anions with derivatives of cyclic anhydrides or oxidative cleavage of cyclic allyl phosphine oxides gives Ph 2 PO-ketoacids: reduction, separation of diastereoisomers, and completion of the Horner-Wittig reaction gives single isomers (Full-size image (< 1 K)