Helvetica Chimica Acta

A Novel Synthesis of Isoflavones via Copper (I)??Catalyzed Intramolecular Cyclization Reaction

QL Li, QL Liu, ZY Ge, YM Zhu

Index: Li, Qiu-Lian; Liu, Qi-Lun; Ge, Zhi-Yuan; Zhu, Yong-Ming Helvetica Chimica Acta, 2011 , vol. 94, # 7 p. 1304 - 1309

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Citation Number: 7

Abstract

Abstract Isoflavone derivatives were synthesized via intramolecular cyclization of 3-(2- bromophenyl)-3-oxopropanal derivatives, using CuI as the catalyst, 2-picolinic acid (= pyridine-2-carboxylic acid) as the ligand, K 2 CO 3 as the base, and DMF as the solvent, in