Abstract The preparative method for the synthesis of 2-fluoroadenosine starting from commercially available guanosine was developed. It included the intermediate formation of 2-amino-6-azido-9-(2, 3, 5-tri-O-acetyl-β-D-ribofuranosyl) purine, which was isolated exclusively in the tetrazolo [5, 1-i]-form {5-amino-7-(2, 3, 5-tri-O-acetyl-β-D-ribofuranosyl)-7 H- tetrazolo [5, 1-i] purine}. The latter compound was converted by the Schiemann reaction to ...
