Synthesis

Unexpected formation of benzothiazoles in the synthesis of new heterocycles: benzo-1, 2, 4-dithiazines

D Fajkusova, P Pazdera

Index: Fajkusova, Dagmar; Pazdera, Pavel Synthesis, 2008 , # 8 p. 1297 - 1305

Full Text: HTML

Citation Number: 18

Abstract

Abstract The synthesis of benzo-1, 2, 4-dithiazines was investigated presuming a reversible sulfur-sulfur bond formation. 2-Aminothiophenol, when allowed to react with isothiocyanates, provided benzothiazoles. 2, 2′-Diaminodiphenyl disulfide underwent cyclizations very readily without any reducing agent to give, according to the reaction conditions, benzothiazoles or benzo-1, 2, 4-dithiazines. The developed procedure offers a simple and ...