Dictyostatin flexibility bridges conformations in solution and in the β-tubulin taxane binding site

AS Jogalekar, K Damodaran, FH Kriel…

Index: Paterson, Ian; Naylor, Guy J.; Fujita, Takeshi; Guzman, Esther; Wright, Amy E. Chemical Communications, 2010 , vol. 46, # 2 p. 261 - 263

Full Text: HTML

Citation Number: 16

Abstract

... ring structure, was proposed by analysis of three-bond proton−proton couplings ( 3 J H−H ... in this data set, we searched the conformational pool with rapid overlay of chemical structures (ROCS ... NMR Data The NMR data for dictyostatin in methanol-d 4 were those of Paterson et al ...