Lithium pipecolinate as a facile and efficient ligand for copper-catalyzed hydroxylation of aryl halides in water

…, J Wei, L Zhou, Z Huang, Z Li, X Zhou

Index: Jing, Linhai; Wei, Jiangtao; Zhou, Li; Huang, Zhiyong; Li, Zhengkai; Zhou, Xiangge Chemical Communications, 2010 , vol. 46, # 26 p. 4767 - 4769

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Citation Number: 53

Abstract

Phenols are not only important structural motifs occurring in numerous pharmaceuticals, polymers, and natural products, but also serve as versatile synthetic intermediates in preparing oxygenated heterocycles 1 and aryl ethers. 2 The classical non-oxidative preparation of this class of compounds include transformation of arene diazonium salts in the presence of a copper complex, nucleophilic substitution of activated aryl halides and the benzyne synthetic ...