Abstract The boronic acid group is an important recognition moiety for sensor design. Herein, we report a series of isoquinolinylboronic acids that have extraordinarily high affinities for diol-containing compounds at physiological pH. In addition, 5-and 8- isoquinolinylboronic acids also showed fairly high binding affinities towards D-glucose (K a= 42 and 46 M− 1, respectively). For the first time, weak but encouraging binding of cis- ...
