Synthesis of bicyclic σ receptor ligands with cytotoxic activity

C Geiger, C Zelenka, M Weigl, R Fröhlich…

Index: Weigl, Manuela; Wuensch, Bernhard Tetrahedron, 2002 , vol. 58, # 6 p. 1173 - 1183

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Citation Number: 33

Abstract

All possible stereoisomeric alcohols (6-benzyl-8-(4-methoxybenzyl)-6, 8-diazabicyclo [3.2. 2] nonan-2-ol) and methyl ethers (6-benzyl-2-methoxy-8-(4-methoxybenzyl)-6, 8-diazabicyclo [3.2. 2] nonane) are prepared from (R)-and (S)-glutamate. A Dieckmann analogous