Indapamide (1) (indole derivative) is the international non-proprietary name of the chemical product 4-chloro-3- sulphamoyl -N- ( 2 , 3 - dihydro - 2 - methyl - 1H- indol - 1 - yl )- benzamide. Indapamide (1) is an oral antihypertensive/ diuretic, which is indicated for the treatment of hyperten- sion, alone or in a combination with other antihypertensive drugs [1]. In the literature, several methods for the preparation of this compound have been already described. According to the ...
