Broadly Applicable Z??and Diastereoselective Ring??Opening/Cross??Metathesis Catalyzed by a Dithiolate Ru Complex

…, RKM Khan, S Torker, AH Hoveyda

Index: Koh, Ming Joo; Khan, R. Kashif M.; Torker, Sebastian; Hoveyda, Amir H. Angewandte Chemie - International Edition, 2014 , vol. 53, # 7 p. 1968 - 1972 Angew. Chem., 2014 , vol. 126, # 7 p. 1999 - 2003,5

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Citation Number: 34

Abstract

Abstract A broadly applicable Ru-catalyzed protocol for Z-selective ring-opening/cross- metathesis (ROCM) is disclosed. In addition to reactions relating to terminal alkenes of different sizes, the first examples of Z-selective ROCM processes involving heteroaryl olefins, 1, 3-dienes, and O-and S-substituted alkenes as well as allylic and homoallylic alcohols are reported. Z-Selective transformations with an α-substituted allylic alcohol are ...