Indolin-2-one p38α inhibitors II: Lead optimisation

P Eastwood, J González, E Gómez, F Caturla…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 18 p. 5270 - 5273

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Citation Number: 9

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 1. In a previous Letter, 2 the design, synthesis and binding mode (as determined by X-ray crystallography) of a series of indolin-2-one based p38α inhibitors, as exemplified by 1 (Fig. 1), was described. ...