The mechanistic details of the Pd (II)/(-)-sparteine-catalyzed aerobic oxidative kinetic resolution of secondary alcohols were elucidated, and the origin of asymmetric induction was determined. Saturation kinetics were observed for rate dependence on [(-)-sparteine]. First-order rate dependencies were observed for both the Pd ((-)-sparteine) Cl2 concentration and the alcohol concentration at high and low [(-)-sparteine]. The oxidation ...
