Abstract In an effort to establish new candidates with improved analgesic and anti- inflammatory activities, we reported here the synthesis and in-vivo analgesic and anti- inflammatory evaluation of various series of 2-substituted-3a, 4, 9, 9a-tetrahydro-4, 9-
![2-hydroxy-3a,4,9,9a-tetrahydro-4,9-[1,2]benzeno-1H-benzo[f]isoindole-1,3(2H)-dione Structure](https://image.chemsrc.com/caspic/355/121386-99-0.png)